Health and Armor are mainly the types of Seals used. Like Marks, you can buy 9 of them, and these are mostly for boosting your Champion’s defensive capabilities. Buy Marks that boost attack or ability power or even armor or magic penetration, depending on your preference. You can buy a total of 9 Marks, and these are mainly for boosting your Champion’s offensive abilities.
Runes have four types, and each type has an attribute that give you an idea on which to buy for your page:
You can’t spend RP (Riot Points, or as we all know it…real money) to buy Runes, so if you want really good ones and a complete set, you need to prepare yourself for the grind. They can only be purchased in the in-client Store with Influence Points (you earn IP by playing games, so if you want a lot of IP, play more games!). Runes are magical blessings you can give to your Champion before they go into a match. Let’s get in depth and try to make sense of what all these are and how to make the most of them so you can play efficiently. In a way, yes, the way your Summoner profile works is kind of like an RPG. “Why do I have a level?! What is this, an RPG?!”
I’m sure the first time you looked at your profile in the in-game client, you went: “What the hell are these?!”